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Peptide and supplement research, sourced and dated.

We publish what the evidence actually supports, with the source attached to every claim. Nothing here recommends a compound, a dose, or a schedule.

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Why one unapproved compound has 39 trials

A trial count can be inflated by how a compound is developed rather than how much is known about it. This is the clearest example on the site.Reviewed Aug 1, 20265 minRegulatory sources · 3 sourcesCagrilintideSemaglutidePramlintide Peptide basics

Four things in this peptide directory are not peptides

Peptide has become a marketing category rather than a chemical one, and four compounds on this site prove it.Reviewed Aug 1, 20265 minRegulatory sources · 3 sourcesMK-677EnclomipheneOrforglipron+1 Peptide basics

Some compounds here have no trials, no papers and almost no readers

The site tracks four independent things for each compound. A handful score close to zero on all of them, and are sold anyway.Reviewed Jul 31, 20265 minRegulatory sources · 4 sourcesAOD-9604AdipotideFollistatin 344+1 Peptide basics

The placebo group was not doing nothing

Half of every trial is the comparison group, and what that group received decides what the headline number actually means.Reviewed Jul 31, 20265 minPrimary trials · 3 sourcesSemaglutideTirzepatide Peptide basics

The famous gut peptide has 162 participants. The obscure one has 1,211

Two peptides studied for the gut lining. One of them you have heard of, and it is not the one with the evidence.Reviewed Jul 30, 20265 minRegulatory sources · 3 sourcesBPC-157Larazotide Peptide basics

The way around the swallowing problem was to stop using a peptide

Peptides are hard to swallow because of what they are. One solution was to build something that hits the same target and is not one.Reviewed Jul 30, 20265 minRegulatory sources · 3 sourcesOrforglipronSemaglutideTirzepatide Buying and sourcing

Research use only is a sentence about the seller, not the product

It is the most common phrase in this market and one of the most widely misread. It describes intent, not quality.Reviewed Jul 29, 20265 minRegulatory sources · 3 sourcesBPC-157TB-500Epithalon Peptide basics

Four unapproved GLP-1 compounds have already enrolled 65,000 people

Not approved does not mean not studied. Four compounds in this class have larger evidence bases than most approved peptides on this site.Reviewed Jul 29, 20266 minRegulatory sources · 4 sourcesRetatrutideCagrilintideSurvodutide+1 Peptide basics

1,380 papers and 44 people: the antimicrobial peptide gap

Antimicrobial peptides are one of the most active areas in peptide research and one of the least translated into human trials.Reviewed Jul 28, 20265 minRegulatory sources · 3 sourcesLL-37KPVThymosin alpha-1 Peptide basics

An empty registry can mean 1990, not nothing

One compound on this site is FDA-approved with a completely empty trial record. The reason is a date, and it changes how the gap should be read.Reviewed Jul 28, 20265 minRegulatory sources · 3 sourcesSermorelinGonadorelinOxytocin Peptide basics

One is approved but discontinued. The other is not a peptide

Both are sold for the same reason and neither is what a buyer usually assumes. The details are unusually worth knowing.Reviewed Jul 27, 20265 minRegulatory sources · 4 sourcesEnclomipheneGonadorelinKisspeptin-10 Peptide basics

Eleven trials, 1,215 people, and then it stopped

Some compounds are unstudied. This one was studied properly, in over a thousand people, and then everybody walked away.Reviewed Jul 27, 20265 minRegulatory sources · 3 sourcesTesofensineAdipotideAOD-9604 Peptide basics

Neither has a registered trial, and one nearly got a disambiguation page

Two sleep and mood peptides with no registered human trials between them, and a cautionary tale about how their numbers get produced.Reviewed Jul 26, 20265 minRegulatory sources · 3 sourcesSelankDSIPSemax Peptide basics

1,368 papers, nine trials: the pattern that repeats for every body-made peptide

A molecule your own body makes will always have an enormous literature. Almost none of it is about giving it to someone.Reviewed Jul 26, 20265 minRegulatory sources · 3 sourcesVasoactive intestinal peptideOxytocinGlutathione Peptide basics

Tesamorelin has 18 trials and an approval. CJC-1295 has one trial

Both are growth hormone releasing hormone analogues. One completed development and one is mostly known from the internet.Reviewed Jul 25, 20265 minRegulatory sources · 4 sourcesCJC-1295TesamorelinSermorelin Peptide basics

A formula is a fact. A mechanism is a claim

Chemical identity data looks like the most solid thing on a compound page. It is — and it answers a much narrower question than people expect.Reviewed Jul 25, 20265 minRegulatory sources · 3 sourcesMGFBPC-157Epithalon Peptide basics

One cognitive peptide has 39 trials. The rest of its category has almost none

The thinnest-evidenced category on this site contains one compound with a substantial trial record. It is worth understanding why that combination exists.Reviewed Jul 24, 20265 minRegulatory sources · 4 sourcesCerebrolysinSemaxSelank Peptide basics

STEP 4 enrolled 902 people and randomised 803. The missing 99 matter

Two numbers on the same registry record disagree, and the disagreement is deliberate. It is also the reason the result reads better than it otherwise would.Reviewed Jul 24, 20265 minPrimary trials · 3 sourcesSemaglutide Peptide basics

Oxytocin has 648 trials. Almost none of them are about what it is sold for

This is the best-evidenced compound on the entire site, and its evidence base is a warning about how evidence gets borrowed.Reviewed Jul 23, 20265 minRegulatory sources · 3 sourcesOxytocinKisspeptin-10Gonadorelin Peptide basics

Six of seven cognitive peptides here have no human trial at all

The nine categories on this site are not equally evidenced, and the gap between the best and worst is not close.Reviewed Jul 23, 20266 minRegulatory sources · 4 sourcesSemaxGHK-CuSemaglutide Supplement research

Glutathione has 72,118 papers because it is inside every cell you own

These two have the largest literatures on the site by an enormous margin, and almost none of it is about taking them as a supplement.Reviewed Jul 22, 20266 minRegulatory sources · 4 sourcesNAD+GlutathioneSS-31 Peptide basics

Semaglutide weighs 4,114. Aspirin weighs 180. That is why one is a needle

The reason most peptides come as injections is not marketing or convenience. It is that your gut is very good at destroying them.Reviewed Jul 22, 20266 minRegulatory sources · 4 sourcesSemaglutideGlutathioneTesamorelin Peptide basics

Six fields on a trial record tell you almost everything

A registry record looks like a wall of text. Six fields carry most of the meaning, and you can find them all in under two minutes.Reviewed Jul 21, 20267 minRegulatory sources · 4 sourcesSemaglutideTirzepatide Peptide basics

The eleven characters that settle most arguments about peptides

NCT03548935 is not jargon. It is a receipt, and asking for one ends more disputes than any amount of argument.Reviewed Jul 21, 20265 minRegulatory sources · 3 sourcesSemaglutideBPC-157