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April 2026

We publish what the evidence actually supports, with the source attached to every claim. Nothing here recommends a compound, a dose, or a schedule.

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GLP-1 and muscle

What controlled trials actually measured about lean mass on GLP-1s

The large trials reported total body weight. Body composition came from small imaging substudies — and those instruments have limits of their own.Reviewed Jul 18, 20266 minSecondary sources · 7 sourcesSemaglutideTirzepatideLiraglutide