Methodology

Where every number on this page comes from.

Where the numbers come from

Four datasets, all public, all free, each collected by a script in this repository and each carrying the date it was collected and a link to the query that produced it.

• Registered human studies — ClinicalTrials.gov API v2. A search by intervention, then every result re-checked: a study counts only if the compound is named as an intervention in it, in the name or the registered synonyms. The registry search is fuzzy, so this matters. A search for MGF returned 102 studies of which none administered MGF. Each compound page shows how many matches were checked and how many survived, because a count you cannot see the discards from is a count you have to take on faith.
• FDA approval — openFDA, the Drugs@FDA approvals endpoint, matched on active ingredient. Not the label endpoint, which token-matches ingredient lists and once reported a topical cream as evidence that two cosmetic peptides were FDA-approved.
• Publication and trial activity — PubMed E-utilities and ClinicalTrials.gov, ten calendar years. Publication counts are phrase-matched in title and abstract, so a paper mentioning the words separately is not counted. The current year is always incomplete and is drawn hatched rather than quietly included.
• Readership — the Wikimedia pageviews API, averaged over the last six complete calendar months. Part-months are discarded: an earlier version averaged a single day in as though it were a month and published every figure on the site roughly 17% low.

What the evidence grade is

The grade is mechanical. It is computed from the registry and the FDA record alone, by this rule and nothing else:

• A — an FDA-approved product contains this compound, and at least one trial of it is registered.
• E — an FDA-approved product exists, but no trial of it is registered. Sermorelin is the only one: approved in 1990, before trial registration was mandatory. Approval alone is not evidence of how much has been studied, which is what this column grades.
• B — reached phase 3 or phase 4, without FDA approval.
• C — reached phase 1 or phase 2 only.
• D — has registered studies, none of which record a phase.
• X — no registered human study at all.

It grades how much is known, never whether a compound works or is safe. A compound can be well studied and ineffective, and an X is a statement about the public record rather than about the molecule.

What “readership” means

It counts people opening the English Wikipedia article about a compound. It is not search volume, not sales, and not demand. Someone reading an encyclopedia article has looked something up, and nothing more. A rise means more people are curious; it says nothing about whether a compound works, whether it is legal to buy, or how many people take it.

It is used to order the table because it is a real measured quantity and the alternatives were not. No provider publishes absolute search volume for these terms, so any site showing you “347,000 searches this week” for a peptide is showing you a number it invented or bought from a model that estimated it.

What the vendor columns mean

The vendor table records what a vendor discloses: whether a certificate of analysis is published, whether an independent testing lab is named, whether batch numbers appear on the label, whether a business address is published, and where the vendor says it ships from.

These are not a quality, safety or legitimacy rating. We have not tested any product, we cannot confirm that what a vendor ships matches what it lists, and a published document is not proof that the document describes the vial you receive. There is deliberately no composite “trust score” on this site, because a single number would imply a verification we have not performed.

Affiliate links

Vendor links are not affiliate links. PepRack earns nothing on a peptide and links to no compound seller for money, so no commercial relationship influences which vendors are listed or how the table is ordered — it sorts on the figures you choose. The site does earn commission on supplies and equipment, and those links are the only paid links on it: they are marked rel="sponsored nofollow", sit on a visually distinct surface, and are labelled as paid wherever they appear. Full detail is in the affiliate disclosure.

Current coverage

As of the most recent collection run: 68 compounds in the directory, 0 with at least one observed price, 0 vendors tracked, 0 price observations recorded.

Corrections

If a price is wrong, a vendor is misrepresented, or a compound is miscategorised, write to help@peprack.com. Include the page and the date shown beside the figure.

Nothing on this site is medical advice. PepRack does not recommend a compound, a dose, a schedule, an injection method, or a treatment, and price information is not a suggestion to buy.