Category
Weight loss & metabolic
GLP-1 and dual-agonist chemistry. By a wide margin the best-evidenced group here — it holds most of the approved products on the site and the largest trial populations, and it is the only category where the main question is which compound rather than whether any of them have been studied.
What the record holds for this category
19
Compounds tracked
9
With an FDA-approved product
4
With no registered human study
1,931
Registered studies, all members
Every compound in this category
Ordered by how many people read the Wikipedia article each month, which measures attention and nothing else. The evidence column is what is actually known.
| Compound | FDA status | Human studies | Evidence | Readership |
|---|---|---|---|---|
| Semaglutide | Approved | 589 | AAn approved product exists | 54,466 |
| Retatrutide | Research only | 20 | BReached phase 3 or 4, not approved | 49,387 |
| Tirzepatide | Approved | 222 | AAn approved product exists | 38,322 |
| Orforglipron | Approved | 33 | AAn approved product exists | 9,289 |
| Liraglutide | Approved | 442 | AAn approved product exists | 4,759 |
| SLU-PP-332 | Research only | 0 | XNo registered human study | 4,136 |
| MOTS-c | Research only | 1 | CPhase 1 or 2 only | 4,082 |
| Tesofensine | Research only | 11 | CPhase 1 or 2 only | 3,235 |
| Exenatide | Approved | 279 | AAn approved product exists | 3,088 |
| Cagrilintide | Research only | 39 | BReached phase 3 or 4, not approved | 2,936 |
| Dulaglutide | Approved | 115 | AAn approved product exists | 2,756 |
| Survodutide | Research only | 23 | BReached phase 3 or 4, not approved | 1,155 |
| Mazdutide | Research only | 12 | BReached phase 3 or 4, not approved | 1,109 |
| Setmelanotide | Approved | 25 | AAn approved product exists | 972 |
| Pramlintide | Approved | 54 | AAn approved product exists | 628 |
| Lixisenatide | Approved | 66 | AAn approved product exists | 462 |
| Adipotide | Research only | 0 | XNo registered human study | 58 |
| AOD-9604 | Research only | 0 | XNo registered human study | 26 |
| 5-Amino-1MQ | Research only | 0 | XNo registered human study | — |
Compare within this category
These pairs are the most-read members, picked mechanically. Pairing is not a recommendation and says nothing about which is preferable.
Reading on these compounds
Categories are editorial groupings by mechanism — they are not medical classifications, and membership is not a claim that a compound does what the group name suggests. Study counts include only trials whose registered intervention names the compound. Collected 2026-08-02 from ClinicalTrials.gov and Drugs@FDA. How this is put together.