NOOP

Noopept

A small molecule rather than a plain peptide: the ethyl ester of N-phenylacetyl-L-prolylglycine, a dipeptide with a phenylacetyl group on the nitrogen and its carboxyl esterified. Both modifications remove the charges that would keep a bare dipeptide out of tissue. No receptor target has been established in the published literature.

No registered human study names Noopept as an intervention. ClinicalTrials.gov holds no trial of it, so there is no trial evidence to read — a fact about the public record rather than proof the compound does nothing. No FDA-approved product contains Noopept. 21 papers naming it were published in the last ten years.

Collected 2026-08-02 from ClinicalTrials.gov and Drugs@FDA. Counts include only trials whose registered intervention names Noopept; the registry search is fuzzy, so every match is re-checked. None of this says whether Noopept works or is safe.

FDA status

Research only

Human studies

0

Furthest phase

Papers, 10 yr

21

Readership

224

monthly average, Feb–Jul 2026

Tracking since 2026-07-29 · About this data

What has actually been tested in humans

X

No registered human study

0

Registered human studies

None

No FDA-approved product contains it

No study of Noopept in humans is registered on ClinicalTrials.gov. That is a fact about the public record, not a statement that the compound does nothing — but it does mean there is no trial evidence to read, and anyone telling you otherwise should be asked for the registration number. The grade is mechanical: it is computed from the registry and the FDA record alone, and it grades how much is known, never whether a compound is good or safe. Collected 2026-08-02 from ClinicalTrials.gov and Drugs@FDA. Check the query.

What Noopept is, and what it has been studied for

Noopept is tracked here.

No registered trial names Noopept as an intervention, so there is no condition it has been formally studied in. It does have a literature: 21 indexed papers name it in the last ten years. That work is laboratory and animal research, and a paper is not a trial.

Is anyone studying Noopept?

Papers published each year that name Noopept in the title or abstract, with the clinical trials that started in the same year marked beneath. Ten calendar years.

0123417181920212223242526
Vertical axis: papers published that year. Bar for 2026 is hatched because that year is still running.
Publications and trials naming Noopept, by year
YearPublicationsTrials startedComplete year
201700Yes
201840Yes
201940Yes
202020Yes
202140Yes
202220Yes
202310Yes
202420Yes
202520Yes
202610No

21 papers between 2017 and 2026. A paper counts when “Noopept” appears in its title or abstract — phrase-matched, so a paper mentioning the words separately is not counted. The total is a single query over the whole window, which is why it does not equal the bars added together: PubMed files a paper under both its electronic and its print publication date, so one paper can appear in two years. Publication volume measures scientific attention, not whether a compound works: a well-studied compound can be well-studied and ineffective. Sources: PubMed and ClinicalTrials.gov · collected 2026-08-02.

Published research on Noopept

21 indexed papers name Noopept in their title or abstract. These are the 8 PubMed ranks most relevant. Listing a paper is not a judgement about it, and none of these is summarised here — follow the link and read what it says.

  1. Effects of noopept on ocular, pancreatic and renal histopathology in streptozotocin induced prepubertal diabetic rats

    Gurbuz P, Duzova H, Taslidere AC, et al.Biotechnic & histochemistry : official publication of the Biological Stain Commission2023

    PMID 3694617310.1080/10520295.2023.2187460

  2. Cognitive Enhancer Noopept Activates Transcription Factor HIF-1

    Zainullina LF, Ivanova TV, Sadovnikov SV, et al.Doklady. Biochemistry and biophysics2020

    PMID 3311982910.1134/S1607672920050129

  3. Effects of noopept on cognitive functions and pubertal process in rats with diabetes

    Gürbüz P, Düzova H, Yildiz A, et al.Life sciences2019

    PMID 3135690610.1016/j.lfs.2019.116698

  4. The original novel nootropic and neuroprotective agent noopept

    Ostrovskaia RU, Gudasheva TA, Voronina TA, et al.Eksperimental'naia i klinicheskaia farmakologiia2002

    PMID 12596521

  5. Drug with Neuroprotective Properties Noopept Does Not Stimulate Cell Proliferation

    Zainullina LF, Ivanova TV, Ostrovskaya RU, et al.Bulletin of experimental biology and medicine2019

    PMID 3078874610.1007/s10517-019-04373-8

  6. A Mini-review on Unlocking Cognitive Enhancement: An Innovative Strategy for Optimal Brain Functions

    Vikal A, Maurya R, Patel BB, et al.Central nervous system agents in medicinal chemistry2026

    PMID 4066256110.2174/0118715249357704250702140026

  7. Noopept normalizes parameters of the incretin system in rats with experimental diabetes

    Ostrovskaya RU, Zolotov NN, Ozerova IV, et al.Bulletin of experimental biology and medicine2014

    PMID 2506531510.1007/s10517-014-2562-5

  8. Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept

    Vakhitova YV, Sadovnikov SV, Borisevich SS, et al.Acta naturae2016

    PMID 27099787

Collected 2026-08-02from PubMed, phrase-matched on “Noopept” in title and abstract. Run the same search.

About Noopept

A small molecule rather than a plain peptide: the ethyl ester of N-phenylacetyl-L-prolylglycine, a dipeptide with a phenylacetyl group on the nitrogen and its carboxyl esterified. Both modifications remove the charges that would keep a bare dipeptide out of tissue. No receptor target has been established in the published literature.

Also known as
Omberacetam · GVS-111

Structure and mechanism only. Nothing above describes what this compound is for, and no dose appears anywhere on this page.

Reading on this compound

All articles

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