HUMN
Humanin
A 24-amino-acid peptide encoded within the mitochondrial 16S ribosomal RNA gene, one of the mitochondrial-derived peptides. The published work describes activity at a trimeric cell-surface complex of the ciliary neurotrophic factor receptor, WSX-1 and gp130, and separately at formyl peptide receptor-like 1.
No registered human study names Humanin as an intervention. ClinicalTrials.gov holds no trial of it, so there is no trial evidence to read — a fact about the public record rather than proof the compound does nothing. No FDA-approved product contains Humanin. 336 papers naming it were published in the last ten years.
Collected 2026-08-02 from ClinicalTrials.gov and Drugs@FDA. Counts include only trials whose registered intervention names Humanin; the registry search is fuzzy, so every match is re-checked. None of this says whether Humanin works or is safe.
FDA status
Research only
Human studies
0
Furthest phase
—
Papers, 10 yr
336
Readership
671
monthly average, Feb–Jul 2026
Tracking since 2026-07-29 · About this data
What has actually been tested in humans
No registered human study
0
Registered human studies
None
No FDA-approved product contains it
3 loose registry matches were checked and 0 confirmed — 3 named something else and were discarded. We count a study only when Humanin is named as an intervention in it.
No study of Humanin in humans is registered on ClinicalTrials.gov. That is a fact about the public record, not a statement that the compound does nothing — but it does mean there is no trial evidence to read, and anyone telling you otherwise should be asked for the registration number. The grade is mechanical: it is computed from the registry and the FDA record alone, and it grades how much is known, never whether a compound is good or safe. Collected 2026-08-02 from ClinicalTrials.gov and Drugs@FDA. Check the query.
What Humanin is, and what it has been studied for
Humanin is tracked here. Its FDA substance identifier is H975EUX36G.
No registered trial names Humanin as an intervention, so there is no condition it has been formally studied in. It does have a literature: 336 indexed papers name it in the last ten years. That work is laboratory and animal research, and a paper is not a trial.
Is anyone studying Humanin?
Papers published each year that name Humanin in the title or abstract, with the clinical trials that started in the same year marked beneath. Ten calendar years.
| Year | Publications | Trials started | Complete year |
|---|---|---|---|
| 2017 | 30 | 0 | Yes |
| 2018 | 31 | 0 | Yes |
| 2019 | 36 | 0 | Yes |
| 2020 | 41 | 0 | Yes |
| 2021 | 44 | 0 | Yes |
| 2022 | 40 | 0 | Yes |
| 2023 | 41 | 0 | Yes |
| 2024 | 41 | 0 | Yes |
| 2025 | 37 | 0 | Yes |
| 2026 | 40 | 0 | No |
336 papers between 2017 and 2026. A paper counts when “Humanin” appears in its title or abstract — phrase-matched, so a paper mentioning the words separately is not counted. The total is a single query over the whole window, which is why it does not equal the bars added together: PubMed files a paper under both its electronic and its print publication date, so one paper can appear in two years. Publication volume measures scientific attention, not whether a compound works: a well-studied compound can be well-studied and ineffective. Sources: PubMed and ClinicalTrials.gov · collected 2026-08-02.
Published research on Humanin
336 indexed papers name Humanin in their title or abstract. These are the 8 PubMed ranks most relevant. Listing a paper is not a judgement about it, and none of these is summarised here — follow the link and read what it says.
- Mitochondrial stress and mitokines in aging
- Humanin: Functional Interfaces with IGF-I
- The role of humanin in the regulation of reproduction
- HUMANIN produced by human efferocytic macrophages promotes the resolution of inflammation
- Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer's disease
- Humanin and the receptors for humanin
- Humanin: A mitochondria-derived peptide with emerging properties
- Humanin: after the discovery
Collected 2026-08-02from PubMed, phrase-matched on “Humanin” in title and abstract. Run the same search.
About Humanin
A 24-amino-acid peptide encoded within the mitochondrial 16S ribosomal RNA gene, one of the mitochondrial-derived peptides. The published work describes activity at a trimeric cell-surface complex of the ciliary neurotrophic factor receptor, WSX-1 and gp130, and separately at formyl peptide receptor-like 1.
- Also known as
- HN · Rattin
Structure and mechanism only. Nothing above describes what this compound is for, and no dose appears anywhere on this page.
Reading on this compound
All articles →PepRack articles that reference this compound. This is not a news feed — we syndicate nothing and publish no datelines.
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